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1. Key T. J., Schatzkin A, Willett W. C., Allen N. E., Spencer E. A., Travis R. C. (2003) Diet, nutrition and the prevention of cancer // Annu Rev Physiol 65: 313–332.

Глава 1. Мозг и сон

1. Bielak A. A., Hughes T. F., Small B. J., Dixon R. A. (2007) It’s never too late to engage in lifestyle activities: significant concurrent but not change relationships between lifestyle activities and cognitive speed // Gerontol B Psychol Sci Soc Sci Nov; 62 (6): P331–339.

2. Lydic R., McCarley R. W., Hobson J. A. (1984) Forced activity alters sleep cycle periodicity and dorsal raphe discharge rhythm. Am J. Physiol 247 (1 Pt 2): R135–145. Stanford Report, “Remediation training improves reading ability of dyslexic children,” February 25, 2003 ().

3. McDaniel M. A. (2003) Brain-specific nutrients: a memory cure // Nutrition 11–12: 957–975.

4. Bower, B. (1998) To dream, perchance to scan // Science News 153: 44.

Глава 2. Как поддержать работу сердца…

1. Liem A. H., Jukema J. W., van Veldhuisen D. J. (2003) Secondary prevention in coronary heart disease patients with low HDL: What options do we have? // Int J. Cardiol 90 (1): 15–21.

2. National Center for Health Statistics, “Deaths – leading causes,” .

3. Lagergvist B., James S., Stenestrand U., Lindback M., Nilsson T., Wallentin L. (2007) Long-term outcomes with drug-eluting stents versus bare-metal stents in Sweden // NEJM 356 (10): 1009–1019.

4. Enos W. F, Holmes R. H, Beyer J (1953) Coronary disease among United States soldiers killed in action in Korea // JAMA 152: 1090–1093.

5. The Society for Women’s Health Research, “What really claims women’s lives?” .

6. Becker D., Gordon R., Morris P., Yorko J., Gordon J., Li M., Iqbal N. (2008) Simvastatin vs therapeutic lifestyle changes and supplements: Randomized primary prevention trail // Mayo Clin Proc 83: 758–764.

7. Lu Z., Kou W., Du B., Wu Y., Zhao S., Brusco O., Morgan J., Capuzzi D. (2008) Effect of Xuezhikang, an extract from red yeast Chinese rice, on coronary events in a Chinese population with previous myocardial infarction // Amer J. of Card 12 (101): 1689–1693.

8. Gouni-Berthold J., Berthold H. (2002) Policosanol: Clinical pharmacology and therapeutic significance of a new lipid-lowering agent // Amer Heart J. 143 (2): 356–365.

9. Morike E. M. (1996) Vitamin E treatment of patients with coronary disease // Deutsch Med Wochenschr May, 121 (21): A9.

10. Brook J. G., Linn S., Aviram M. (1986) Phosphatidlylinositol raises HDL cholesterol levels in humans // Biochem Med Metabol Biol (35): 31–39.

11. Katsuyuki M., Daviglus M. L., Dyer A. R., Kiang L., Garside D. B., Stamler J., Greenland P. (2001) Relationship of blood pressure to 25-year mortality due to coronary heart disease, cardiovascular diseases, and all causes in young adult men: The Chicago Heart Association detection project in industry // Arch Intern Med 161: 1501–1509.

12. Bolotin H. H. (2007) DXA in vivo BMD methodology: An erroneous and misleading research and clinical gauge of bone mineral status, bone fragility, and bone remodelling // Bone 41 (1): 138–154.

Глава 3. Пищеварение

1. Drossman D. A., Li Z., Andruzzi E., Temple R. D., Talley N. J., Thompson W. G., Whitehead W. E., Janssens J., Funch-Jensen P., Corazziari E. et al. (1993) U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodermography, and health impact // Digestive Disease Science 38 (9): 1569–1580.

2. Krasinski S. D., Russell R. M., Samloff I. M., Jacob R. A., Dallal G. E., McGandy R. B., Hartz S.C. (1986) Fundic atrophic gastritis in an elderly population // J. Am Geriatr Soc 34 (11): 800–806.

3. Scrimshaw N. S., Murray E. B. (1988) The acceptability of milk and milk products in populations with a high prevalence of lactose intolerance // Am J. Clin Nutr 48 (Suppl 4): 1079–1159.

4. Swagerty D. L. Jr, Walling A. D., Klein R. M. (2002) Lactose intolerance // Amer Fam Physician 65 (9): 1845–1850.

Глава 4. Оптимизация гормонального фона

1. Canaris G. J., Manowitz N. R., Mayor G., Ridgeway E. G. (2000) The Colorado thyroid prevalence study // Arch of Int. Med (160): 526–534.

2. Svec F., Porter J. R. (1998) The actions of exogenous dehydroepiandrosterone in experimental animals and humans // Proceedings of the Society for Exp Bio and Med (218): 174–191.

3. Lemon J. A., Boreham D. R., Rollow C. D. (2003) A dietary supplement abolishes age-related cognitive decline in transgenic mice expressing elevated free radical processes // Exp Bio Med. (228): 800–810.

4. Butler R. N., Fossel M., Mitchell H., Heward C. B., Olshansky S. J., Perls T. T., Rothman D. J., Rothman S. M., Warner H. R., West M. D., and Wright W.F. (2002) Is there an anti-aging medicine? // J. of Gerontology Series A: Bio SciMed Sci (57): B333-B3385.

5. Straub R. H., Lehle K., Herfarth H., Weber M., Falk M. W., Preuner J., Scholmerich J. (2002) Dehydroepiandrosterone in relation to other adrenal hormones during an acute inflammatory stressful disease state compared with chronic inflammatory disease: Role of interleukin-6 and tumour necrosis factor // Eur J. Endo 146: 365–374.

6. National Sleep Foundation, “Epidemic of Daytime Sleepiness Linked to Increased Feelings of Anger, Stress, and Pessimism,” .

7. Leger D., Laudon M., Zisapel N. (2004) Nocturnal 6-sulfatoxymelatonin excretion in insomnia and its relation to the response to melatonin replacement therapy // Am. J. Med. 116:91–95.

8. The Writing Group for the WHI Investigators (2002) Risks and benefits of estrogen plus progestin in healthy post-menopausal women: Principal results of the Women’s Health Initiative randomized controlled trial // JAMA 288 (3): 321–333.

9. The Women’s Health Initiative Steering Committee (2004) Effects of conjugated equine estrogen in postmenopausal women with hysterectomy. The Women’s Health Initiative randomized controlled trial // JAMA 291: 1701–1712.

10. Rossouw J. E., Prentice R. L., Manson J. E., Wu L., Barad D., Barnabei V. M., Ko M., LaCroix A. Z., et al. (2007) Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause // JAMA 297: 1465–1477.

11. Fournier A., Berrino F., Riboli E., Avenel V., and Clavel-Chapelon F. (2005). Риск развития рака молочной железы в связи с различными видами заместительной гормональной терапии в когорте E3N-EPIC // Проблемы репродукции. М.: Медиа Сфера, № 4 (2005).

12. Rudman D., Drinka P. J., Wilson C. R., Mattson D. E., Scherman F., Cuisinier M. C., Schultz S. (1994) Relations of endogenous anabolic hormones and physical activity to bone mineral density and lean body mass in elderly men // Clin Endo 40: 653–661.

13. Stephenson K., Price C., Kurdowska A., Neuenschwander P., Stephenson J., Pinson B., Stephenson D., Alfred D., Krupa A., Mahoney D., Zava D., and Bevan M. (2004) Topical progesterone cream does not increase thrombotic and inflammatory factors in postmenopausal women // ASH Annual Meeting Abstracts 104: 5318.

Глава 5. Метаболические процессы

1. Das UN (2006) Exercise and inflammation // The Euro Heart J. 27 (11): 1385.

2. Fenech M., Aitken C., Rinaldi J. (1998) Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults // Carcinogenesis 19 (7): 1163–1171.

Глава 6. Онкологические заболевания

1. American Cancer Society, “Cancer Facts and Figures,” .

2. American Cancer Society, “Costs of Cancer,” .

3. Key T. J., Schatzkin A., Willett W. C., Allen N. E., Spencer E. A., Travis R. C. (2004) Diet, nutrition and the prevention of cancer // Pub Health Nutr Feb 7 (1A): 187–200.

4. Trichopoulou A., Costacou T., Bamia C., Trichopoulos D. (2003) Adherence to a Mediterranean diet and survival in a Greek population // N Engl J. Med 348 (26): 2599–2608.

5. Dominique M. S., Simin L., Giovannucci E., Willett W. C., Graham C. A., Fuchs C. S. (2002) Dietary sugar, glycemic load and pancreatic cancer risk in a prospective study // Natl Can Jnsf 94 (17): 1293–1300.

6. Higginbotham S., Zhang Z. F., Lee I. M., Cook N., Giovannucci E., Buring J. E., Liu S. (2004) Dietary glycemic load and risk of colorectal cancer in the Women’s Health Study // Natl Can Inst 96 (3): 229–233.

7. Calle E. E., Rodrigue C., Walker-Thurmond K., Thun M. (2003) Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults // NEJM 348 (17): 1625–1638.

8. Zheng Q. S., Zheng R. L. (2002) Effects of ascorbic acid and sodium selenite on growth and redifferentiation in human hepatoma cells and its mechanisms // Pharmazie 57 (4): 265–269.

9. Duffield-Lillico A. J., Reid M. E., Turnbull B. W., Combs G. F., Slate E. H., Fischbach L. A., Marshall J. R., Clark L. C. (2002) Baseline characteristics and the effect of selenium supplementation on cancer incidence in a randomized clinical trial // Cancer Epidemiol Biomarkers Prev 11: 630–639.

10. Lappe J. M., Travers-Gustafson D. T., Davies K. M., Recker R. R., Heaney R. P. (2007) Vitamin D and calcium supplementation reduces cancer risk: Results of a randomized trial // Amer J. of Clin Nutr 85 (6): 1586–1591.

11. Eichholzer M., Luthy J., Moser U., Fowler B. (2001) Folate and the risk of colorectal, breast and cervix cancer: The epidemiological evidence // Swiss Med Wkly 131: 539–54.

Глава 7. Геномика

1. Kathiresan S., Melander O., Anevski D., Guiducci C., Burtt N. P., Roos C., Hirschhorn J. N., Berglund G., Hedblad B., Groop L., Altshuler D. M., Newton-Cheh C., Orho-Melander M. (2008) Polymorphisms associated with cholesterol and risk of cardiovascular events // N Engl J. Med. 358 (12): 1240–1249.

2. Love-Gregory L., Sherva R., Sun L., Wasson J., Schappe T., Doria A., Rao D. C., Hunt S. C., Klein S., Neuman R. J., Permutt M. A., Abumrad N. A. (2008) Variants in CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol // Human Molecular Genetics 17 (11): 1695–1704.

Глава 8. Разговор с лечащим врачом

1. National Center for Health Statistics, “Deaths – leading causes,” .

Глава 9. Релаксация

1. Holmes T., Rahe R. (1967) The social readjustment rating scale // Psychosom Res 11 (2): 213–218.

2. Weber G. (2004) Weber G. (2004) Lost time: Vacation days go unused despite more liberal time-off policies. Workforce Man. Dec: 66–67 .

3. Haskell C. F., Kennedy D. O., Milne A. L., Wesnes K. A., Scholey A. B. (2008) The effects of 1-the-anine, caffeine and their combination on cognition and mood // Bio Psych 77 (2): 113–122.

4. Zaret B. L., Moser M., Cohen L. S. (1992) Yale University School of Medicine Heart Book .

5. Moyer C. A., Rounds J., Hannum J. W. (2004) A meta-analysis of massage therapy research // Psych Bull 130 (1): 3–18.

6. Benson H., Beary J. F., Carol M. P. (1974) The relaxation response // Psychiatry 37 (l): 37–46.

7. Klag M. J, Wang N. Y., Meoni L. A., Brancati F. L., Cooper L. A., Liang K. Y., Young J. H., Ford D. E. (2002) Coffee intake and risk of hypertension: The Johns Hopkins precursors study // Arch Intern Med 162 (6): 657–662.

8. El Yacoubi M., Ledent C., Parmentier M., Costentin J., Vaugeois J.M. (2000) The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists // Psychopharmacology (Berl) 148 (2): 153–163.

9. Haskell C. F., Kennedy D. O., Milne A. L., Wesnes K. A., Scholey A. B. (2007) The effects of L-theanine, caffeine and their combination on cognition and mood // Biol Psychol 77 (2): 113–122.

Глава 10. Оценка состояния организма

1. van Dam R. M., Li T., Spiegelman D., Franco O. H., Hu F. B. (2008) Combined impact of lifestyle factors on mortality: Prospective cohort study in US women // BMJ 337: al 440.

2. Kosters J. P., Gotzsche P. C. (2003) Regular self-examination or clinical examination for early detection of breast cancer // Cochrane Database of Systematic Reviews 2: CD003373. .

Глава 11. Питание

1. O’Keefe J. H., Gheewala N. M., O’Keefe J. O. Стратегия правильного питания в целях улучшения показателей постпрандиальных уровней глюкозы и липидов, устранения воспаления и улучшения состояния сердечно-сосудистой системы // JACC, Т. 2 № 4, 2009, С. 164–170.

2. MedWireNews, September 28, 2007, “Alcohol amount, not type, affects breast cancer risk”.

3. Sesso H. D., Paffenbarger Jr. R. S., Lee I. M. (2001) Alcohol consumption and risk of prostate cancer: The Harvard Alumni Health Study // Int J of Epi 30: 749–755.

4. Johnston C. S., Kim C. M., Buller A. J. (2004) Vinegar improves insulin sensitivity to a high-carbohydrate meal in subjects with insulin resistance or type 2 diabetes // Diabetes Care 27: 281–282.

Глава 12. БАДы

1. Ames B. N., Wakimoto P. (2002) Are vitamin and mineral deficiencies a major cancer risk? // Nature Reviews Cancer 2: 694–704.

2. University Medical Center Rotterdam, “The Rotterdam Study,” .

3. Losonczy K. G., Harris T. B., Havlik R. J. (1996) Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: The Established Populations for Epidemiologic Studies in the Elderly // Am J. Clin Nutr 64 (2): 190–196.

4. Li H., Stampfer M. J., Giovannucci E. L., Morris J. S., Willett W. C., Gaziano J.M., Ma J. (2004) A prospective study of plasma selenium levels and prostate cancer risk // J. Natl Cancer Inst 96 (9): 696–703.

5. Miller E. R., Pastor-Barriuso R., Dalai D., Riemersma R. A., Appel L. J., Guallar E. (2005) Metaanalysis: High-dosage vitamin E supplementation may increase all-cause mortality // Ann Intern Med 142: 37–46.

6. Ames B. N., Elson-Schwab I., Silver E. A. (2002) High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased Km): Relevance to genetic disease and polymorphisms // Amer J. of Clin Nut 75 (4): 616–658.

7. Chen Q., Espey M. G., Sun A. Y., Pooput C., Kirk K. L., Krishna M. C., Khosh D. B., Drisko J., Levine M. (2008) Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice // Pro c Natl Acad Sci USA. 105 (32): 11105–11109.

8. Bjelakovic G., Nikolova D., Gluud L. L., Simonetti R. G., Gluud C. (2007) Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis // JAMA 297 (8): 842–857.

9. Willett W. C., Stampfer M. J. (2001) Clinical practice. What vitamins should I be taking, doctor? // N Engl J. Med 345 (25): 1819–1824.

10. Portakal O., Ozkaya O., Erden Inal M., Bozan B., Kosan M., Sayek I. (2000) Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients // Clin Biochem 33 (4): 279–284.

11. Bagchi D., Bagchi M., Stohs S., Ray S. D., Sen C. K., Preuss H. G. (2002) Cellular protection with proanthocyanidins derived from grape seeds // Ann NY Acad Sci 957: 260–270.

12. Baur J. A., Pearson K. J., Price N. L., Jamieson H. A., Lerin C., Kalra A., Prabhu V. V., Allard J. S., Lopez-Lluch G., Lewis K., Pistell P. J., Poosala S., Becker K. G., Boss O., Gwinn D., Wang M., Ramaswamy S., Fishbein K. W., Spencer R. G., Lakatta E. G., Le Couteur D., Shaw R. J., Navas P., Puigserver P., Ingram D. K., de Cabo R., Sinclair D. A. (2006) Resveratrol improves health and survival of mice on a high-calorie diet // Nature 444 (7117): 337–342.

Глава 13. Уменьшение калорийности рациона и снижение веса

1. National Institute of Diabetes and Digestive and Kidney Disease, Statistics Related to Overweight and Obesity, .

2. Cummings D. E., Weigle D. S., Frayo R. S., Breen P. A., Ma M. K., Dellinger P., Purnell J. Q. (2002) Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery // NEJM 346 (21): 1623–1630.

3. Allison D. B., Miller R. A., Austad S. N., Bouchard C., Leibel R., Klebanov S., Johnson T., Harrison D. E. (2001) Genetic variability in responses to caloric restriction in animals and in regulation of metabolism and obesity in humans // Gerontol A Biol Sci Med Sci 56 Spec № 1: 55–65.

4. Masoro E. J., Yu B. P., Bertrand H. A. (1982) Action of food restriction in delaying the aging process // Proc Natl Acad Sci USA 79 (13): 4239–4241.

Глава 14. Физическая нагрузка

1. Kokkinos P., Myers J., Kokkinos J. P., Pittaras A., Narayan P., Manolis A., Karasik P., Green-berg M., Papademetriou V., Singh S. (2007) Exercise capacity and mortality in black and white men // Circulation 117: 589–591.

2. Cherkas L. F., Hunkin J. L., Kato B. S., Richards B., Gardner J. P., Surdulescu G. L., Kimura M., Lu X., Spector T. D., Aviv A. (2008) The association between physical activity in leisure time and leukocyte telomere length. Arch Int Med 168 (2): 154–158.

3. Reeves N. D., Narici M. V., Maganaris C. N. (2006) Myotendinous plasticity to ageing and resistance exercise in humans // Exp Physiol 91 (3): 483–498.

4. Kraemer W. J., Hakkinen K., Newton R. U., Nindl B. C., Volek J. S., McCormick M., Gotshalk L. A., Gordon S. E., Fleck S. J., Campbell W. W., Putukian M., Evans W. J. (1999) Effects of heavy-resistance training on hormonal response patterns in younger vs. older men // Appl Physiol 87 (3): 982–92.5.

5. Cornelissen V. A., Fagard R. H. (2005) Effect of resistance training on resting blood pressure: A meta-analysis of randomized controlled trials. J. Hypertens 23 (2): 251–259.

6. Henriksson J. (1995) Influence of exercise on insulin sensitivity // Cardiovasc Risk 2 (4): 303–309.

7. Engelke K., Kemmler W., Lauber D., Beeskow C., Pintag R., Kalender W. A. (2006) Exercise maintains bone density at spine and hip EFOPS: A 3-year longitudinal study in early postmenopausal women // Osteoporosis Int 17 (1): 133–142.

Глава 15. Новые технологии

1. De Grey A., Rae M. (2007) Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime. New York: St. Martins Press.

2. Kurzweil, R. (2005) The Singularity Is Near; When Humans TRANSCEND Biology. New York: Viking.

Глава 16. Детоксикация

1. Sundell J. (2004) On the history of indoor air quality and health // Indoor Air 4: 14 Suppl 7: 51–58.

2. Yoder J., Roberts V., Craun G. F., Hill V., Hicks L. A., Alexander N. T., Radke V., Calderon R. L., Hlavsa M. C., Beach M. J., Roy S. L.; Centers for Disease Control and Prevention (CDC) (2008) Surveillance for waterborne disease and outbreaks associated with drinking water and water not intended for drinking – United States, 2005–2006 // MMWR Sur-veill Summ 57 (9): 39–62.

3. Hyland G. J. (2000) Physics and biology of mobile telephony // Lancet 356 (9244): 1833–1836.

4. Beyersmann D., Hartwig A. (2008) Carcinogenic metal compounds: Recent insight into molecular and cellular mechanisms // Arch Toxicol 82 (8): 493–512.